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2-(Trifluoromethyl)aniline → 2-Chloro-6-(trifluoromethyl)aniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(Trifluoromethyl)aniline | HCID 6922 | — |
| 反応物 | Benzenamine, 4-chloro-2-(trifluoromethyl)- | HCID 67961 | — |
| 反応物 | 2,4-Dichloro-6-(trifluoromethyl)aniline | HCID 1268255 | — |
| 生成物 | 2-Chloro-6-(trifluoromethyl)aniline | HCID 2756384 | — |
反応手順
VPC assay of the organic product revealed the following composition (15% XE 60 column packing; 120° C-250° C; 4°/min.): o-aminobenzotrifluoride (13.1 wt. %; 25.94 grams; 0.161 mole; 83.9% conversion); 2-amino-5-chlorobenzotrifluoride, 53.5 wt. %; 105.9 grams or 64.5% corrected yield); and, 2-amino-3,5-dichlorobenzotrifluoride, 33.3 wt. %; 65.93 grams or 34.2% corrected yield). A trace of 2-amino-3-chlorobenzotrifluoride was produced.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04008278 |
| 出典データセット | uspto-grants-1977_02 |
| ORD ID | ord-4ab88bc022c74ed3b3b8242e8e8c522a |
| 出典メモ | uspto-grants-1977_02 |