Ethyl orthoformate → 4-Chloro[1,2,4]triazolo[4,3-a]quinoxaline
反応式
[Cl:1][C:2]1[C:11]([NH:12][NH2:13])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[CH2:14](OC(OCC)OCC)C>>[Cl:1][C:2]1[C:11]2[N:10]([CH:14]=[N:13][N:12]=2)[C:9]2[C:4]([N:3]=1)=[CH:5][CH:6]=[CH:7][CH:8]=2参加物
3
実験手順
A 10 g. portion of 2-chloro-3-hydrazinoquinoxaline was added to 200 ml. of triethylorthoformate and the mixture was rapidly heated to reflux temperature. After 1 hour of heating, with constant stirring, the reaction mixture was cooled and 10.6 g. of product was collected by filtration. The product was identified as 4-chloro-s-triazolo[ 4,3-a]-quinoxaline, m.p. 285°-86° C., by nuclear magnetic resonance analysis and by elemental microanalysis, the results of which follow.
後処理
- temperatureto reflux temperature
- temperatureAfter 1 hour of heating, with constant stirring
- temperaturethe reaction mixture was cooled
- filtrationof product was collected by filtration
- customthe results of which
出典と根拠
- ORDレコード
- ord-92696d79490e43fd9079b21c0d54ed75
- 出典データセット
- uspto-grants-1977_02
- 特許番号
- US04008322
反応ノート
読み込み中…