Hydrochloric Acid → HCID 57023999、化合物

HRID 436438

反応式

HRID 436438 の反応式
[NH:1]([C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH2:6][CH2:5][N:4]=1)[NH2:2].[CH3:13][C:14](=[CH:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH:15]=O.Cl>>[CH3:13][C:14](=[CH:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH:15]=[N:2][NH:1][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH2:6][CH2:5][N:4]=1

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 75572-Methylcinnamic aldehydeHCID 123490411-Hydrazinyl-3,4-dihydroisoquinoline

生成物 1

HCID 57023999HCID 57023999、化合物

実験手順

In a manner similar to that of Example 4, condensation of 1-hydrazino-3,4-dihydroisoquinoline (7.3 g.) and α-methylcinnamaldehyde (6.56 g.) and treatment of the reaction mixture with hydrochloric acid gave a solid, which was recrystallized first from ethanol-ether, then twice from N,N-dimethylformamide-ether, affording 1-[2-(2-methyl-3-phenylallylidene)hydrazino]-3,4-dihydroisoquinoline (I: X=C6H5CH=C(CH3), X'=Y=Y'=Z=Z'=H) hydrochloride in two crops (5.6 g. and 4.2 g., m.p. 217°-219° C.).

後処理

  1. customgave a solid, which
  2. customwas recrystallized first from ethanol-ether

出典と根拠

ORDレコード
ord-918edda720314fb597a19a74bd46d909
出典データセット
uspto-grants-1977_02
特許番号
US04009170

関連ノート

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