化工社化工社 化学情報印刷レポート · 研究参考用
Sulfuric Acid → Ethanol, 2-((4-amino-3-methylphenyl)ethylamino)-, sulfate (1:1)
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | Isopropanol | HCID 3776 | — |
| 反応物 | 4-acetamino-3-methyl-N-(beta-hydroxyethyl)-N-ethylaniline | HCID 21452837 | — |
| 生成物 | Ethanol, 2-((4-amino-3-methylphenyl)ethylamino)-, sulfate (1:1) | HCID 91579 | — |
反応手順
23.6g (0.1 mole) of 4-acetamino-3-methyl-N-(β-hydroxyethyl)-N-ethylaniline were dissolved in 30g of 50% sulfuric acid. The system was reacted for 5 hours at 80° to 100° C while stirring, and then put into 300 ml of isopropyl alcohol and stirred therein while cooling. Crystals separated out, which were then filtered and dried to obtain 22.2g of 4-amino-3-methyl-N-(β-hydroxyethyl)-N-ethylaniline sulfate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04009205 |
| 出典データセット | uspto-grants-1977_02 |
| ORD ID | ord-26995c41f029417ca63be0d687a00f8c |
| 出典メモ | uspto-grants-1977_02 |