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Hydrochloric Acid → 3,3,5-Trimethyl-4-ethoxycarbonyl-5,6-epoxy-cyclohexanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Hydrogen Peroxide | HCID 784 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Ethyl 2,6,6-trimethyl-4-oxocyclohex-2-ene-1-carboxylate | HCID 90877 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 3,3,5-Trimethyl-4-ethoxycarbonyl-5,6-epoxy-cyclohexanone | HCID 21430989 | — |
反応手順
5 g of 3,3,5-trimethyl-4-ethoxycarbonyl-5-cyclohexen-1-one [which can be prepared according to the method described in Example 1] in 800 ml of methanol were cautiously mixed with a solution of 24 ml of a 30% solution of H2O2 and 6 ml of a 6N solution of NaOH. The reaction mixture, after having been stirred for 2 days at room temperature, was neutralized with a diluted HCl solution and the volatile portions were separated by evaporation. Distillation of the residue gave 3,3,5-trimethyl-4-ethoxycarbonyl-5,6-epoxy-cyclohexanone in a pure state.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04028278 |
| 出典データセット | uspto-grants-1977_06 |
| ORD ID | ord-5cf2f964ade4486aa0323b2a5e9ba390 |
| 出典メモ | uspto-grants-1977_06 |