Benzene, 1-isocyanato-4-nitro- → 6-Methyl-2[3-(p-nitrophenyl)ureido]-4-thiocyanatobenzothiazole

HRID 436815

反応式

HRID 436815 の反応式
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([CH3:11])[CH:8]=[C:7]([S:12][C:13]#[N:14])[C:5]=2[N:6]=1.[N+:15]([C:18]1[CH:23]=[CH:22][C:21]([N:24]=[C:25]=[O:26])=[CH:20][CH:19]=1)([O-:17])=[O:16]>CN(C)C=O>[CH3:11][C:9]1[CH:8]=[C:7]([S:12][C:13]#[N:14])[C:5]2[N:6]=[C:2]([NH:1][C:25]([NH:24][C:21]3[CH:20]=[CH:19][C:18]([N+:15]([O-:17])=[O:16])=[CH:23][CH:22]=3)=[O:26])[S:3][C:4]=2[CH:10]=1

参加物

4

反応物 2

HCID 66012Benzene, 1-isocyanato-4-nitro-HCID 124057302-Amino-6-methyl-4-thiocyanatobenzothiazole

生成物 1

HCID 124057346-Methyl-2[3-(p-nitrophenyl)ureido]-4-thiocyanatobenzothiazole

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

A mixture of 2-amino-6-methyl-4-thiocyanatobenzothiazole (35 g., 0.16 mole) in dimethylformamide (250ml.) was treated slowly with p-nitrophenyl isocyanate (27 g., 0.16 mole). The reaction was then heated under stirring on the steam bath for 5 hours. The mixture was then filtered hot. The solution was chilled in an ice bath and filtered. The product was combined with the solid initially filtered to give 40 g. (65%) of off-white solid.

後処理

  1. temperatureThe reaction was then heated
  2. filtrationThe mixture was then filtered hot
  3. temperatureThe solution was chilled in an ice bath
  4. filtrationfiltered
  5. filtrationinitially filtered
  6. customto give 40 g

出典と根拠

ORDレコード
ord-dad3e3216145481aac5d60dfbaffdb3f
出典データセット
uspto-grants-1977_06
特許番号
US04028374

関連ノート

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