2-Thiazolidinone,4-thioxo- → HCID 178508330、化合物

HRID 436858

反応式

HRID 436858 の反応式
[O:1]=[C:2]1[NH:6][C:5](=[S:7])[CH2:4][S:3]1.[NH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11](=N)[NH:10]1>CO>[NH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11](=[C:4]2[S:3][C:2](=[O:1])[NH:6][C:5]2=[S:7])[NH:10]1

参加物

4

反応物 2

HCID 15395952-Thiazolidinone,4-thioxo-HCID 178508669HCID 178508669、化合物

生成物 1

HCID 178508330HCID 178508330、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

To a stirred solution of 49.7 parts of 2-oxo-4-thioxothiazolidine in 990 parts of methanol there was added at 40° C. and under an atmosphere of nitrogen 54.3 parts of powdered 1,3-diiminoisoindoline. Initially, a thick slurry resulted. The reaction mixture was stirred at room temperature for two hours during which time the mixture gradually thinned. The mixture was then heated at reflux for approximately two hours and after cooling to 25° C., was filtered. The collected solid was washed with fresh methanol and dried in vacuo at 50° C. to obtain 1-imino-3-(2-oxo-4-thioxo-5-thiazolidinylidene)isoindoline as an orange powder melting at 267°-8° C. (dec.).

後処理

  1. customInitially, a thick slurry resulted
  2. temperatureThe mixture was then heated
  3. temperatureat reflux for approximately two hours
  4. temperatureafter cooling to 25° C.
  5. filtrationwas filtered
  6. washThe collected solid was washed with fresh methanol
  7. customdried in vacuo at 50° C.

出典と根拠

ORDレコード
ord-22216317c05d493e81fdc0e0761e14fe
出典データセット
uspto-grants-1977_06
特許番号
US04028372

関連ノート

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