Hydrochloric Acid → 10-Methyl-6-oxa-9-undecene-2-one

HRID 436869ノート

反応式

HRID 436869 の反応式
C1CO[C:3]([CH2:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][CH:11]=[C:12]([CH3:14])[CH3:13])([CH3:4])[O:2]1.Cl>CC(C)=O>[CH3:13][C:12]([CH3:14])=[CH:11][CH2:10][CH2:9][O:8][CH2:7][CH2:6][CH2:5][C:3](=[O:2])[CH3:4]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 867348312,2-Ethylenedioxy-10-methyl-6-oxa-9-undecene

生成物 1

HCID 8673483210-Methyl-6-oxa-9-undecene-2-one収率 98.7%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A suspension of 19.7 g of the product of Step A in 100 ml of acetone containing 200 ml of 0.1N hydrochloric acid was stirred at room temperature for 17 hours and the acetone was then evaporated under reduced pressure. The mixture was then extracted with methylene chloride and the organic solution was washed with aqueous sodium bicarbonate solution, then with water, dried over sodium sulfate and evaporated to dryness to obtain 15.7 g of 10-methyl-6-oxa-9-undecene-2-one in the form of a colorless liquid used as is for the next step.

後処理

  1. customthe acetone was then evaporated under reduced pressure
  2. extractionThe mixture was then extracted with methylene chloride
  3. washthe organic solution was washed with aqueous sodium bicarbonate solution
  4. dry with materialwith water, dried over sodium sulfate
  5. customevaporated to dryness

出典と根拠

ORDレコード
ord-12387d8f27c24eb89f5877ec4a9b4343
出典データセット
uspto-grants-1977_06
特許番号
US04028386

反応ノート

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