化工社化工社 化学情報印刷レポート · 研究参考用
Diethyl Ether → 1,1-Diphenyl-3-bromopropan-2-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl Ether | HCID 3283 | — |
| 反応物 | 3-Bromo-1,1-diphenylacetone | HCID 2794635 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 溶媒 | Sodium Hydroxide | HCID 14798 | — |
| 生成物 | 1,1-Diphenyl-3-bromopropan-2-ol | HCID 12549067 | 86% |
反応手順
Sodium borohydride (1 52 g.) in sodium hydroxide solution (15 ml. 0.02M) was added to 1,1-diphenyl-3-bromo-propan-2-one (12 g.) in methanol (50 ml.), and the solution was stirred for one hour. Isolation through ether in the usual manner afforded 1,1-diphenyl-3-bromo-propan-2-ol (10 4 g. 86%) as an oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04028415 |
| 出典データセット | uspto-grants-1977_06 |
| ORD ID | ord-a9f793690624471d99e6cfcd3a65c5a8 |
| 出典メモ | uspto-grants-1977_06 |