Acetic Acid → {[(Benzenesulfinyl)methyl]sulfanyl}benzene

HRID 437111

反応式

HRID 437111 の反応式
C(O)(=[O:3])C.[C:5]1([S:11][CH2:12][S:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.OO.C(=O)([O-])[O-].[K+].[K+]>O.C(Cl)Cl>[C:14]1([S:13][CH2:12][S:11]([C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=2)=[O:3])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

参加物

7

反応物 4

HCID 176Acetic AcidHCID 784Hydrogen PeroxideHCID 11430Potassium CarbonateHCID 770971,1'-(Methylenebis(thio))bis(benzene)

生成物 1

HCID 12743411{[(Benzenesulfinyl)methyl]sulfanyl}benzene収率 96.6%

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 6344Dichloromethane溶媒

実験手順

5 ml of acetic acid was added to 1.538 g of bis(phenylthio)methane, 0.75 ml of an aqueous solution of hydrogen peroxide (concentration: 30%) was added thereto, and then the mixture was stirred for 1 hour at room temperature. After 100 ml of methylene chloride, 6 g of potassium carbonate and a small amount of water were thereto, the resultant mixture was dried with anhydrous sodium sulfate. The product was concentrated under reduced pressure, and then the leavings were separated by means of column-chromatography (silica gel, methylene chloride). Thus 1.585 g of phenyl phenylthiomethyl sulfoxide was obtained as a colorless liquid. The yield was 96.6%.

後処理

  1. additionwas added
  2. dry with materialthe resultant mixture was dried with anhydrous sodium sulfate
  3. concentrationThe product was concentrated under reduced pressure
  4. customthe leavings were separated by means of column-chromatography (silica gel, methylene chloride)

出典と根拠

ORDレコード
ord-5fe393eb309e46adaf0668e4008589b9
出典データセット
uspto-grants-1977_06
特許番号
US04029712

関連ノート

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