Hydrochloric Acid → HCID 21430464、化合物

HRID 437156ノート

反応式

HRID 437156 の反応式
Cl[C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[S:11](=[O:16])(=[O:15])[N:12]([CH3:14])[CH3:13].[NH:17]1[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1.Cl>O>[CH3:13][N:12]([CH3:14])[S:11]([C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:2]=1[N:17]1[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1)[C:6]([OH:8])=[O:7])(=[O:16])=[O:15]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 4837PiperazineHCID 8530794-Chloro-3-(dimethylsulfamoyl)benzoic acid

生成物 1

HCID 21430464HCID 21430464、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

264 Grams of 4-chloro-3-dimethylsulfamoylbenzoic acid (1.0 mole) and 345 g of anhydrous piperazine were heated at 130° C., while stirring, for 1 hour. Subsequently the reaction mixture was dissolved in 2 l of water and the pH value was adjusted to 7 with 5N HCl. After having stood over night, the crystalline precipitate was suction-filtered, washed with water and tetrahydrofurane and recrystallized from water.

後処理

  1. waitAfter having stood over night
  2. filtrationthe crystalline precipitate was suction-filtered
  3. washwashed with water and tetrahydrofurane
  4. customrecrystallized from water

出典と根拠

ORDレコード
ord-6c711e2ed9aa4d059527f452326f9c4c
出典データセット
uspto-grants-1977_06
特許番号
US04029787

反応ノート

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