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N-Pyridin-4-ylacetamide → 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-acetamidopyridinium iodide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-Pyridin-4-ylacetamide | HCID 21288 | — |
| 反応物 | 4-(2-Iodoethyl)-1,2-dimethoxybenzene | HCID 597022 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-acetamidopyridinium iodide | HCID 21413259 | 67.7% |
反応手順
1-(2-Iodoethyl)-3,4-dimethoxybenzene (29.3 g.) and 4-acetamidopyridine (14.0 g.) in absolute ethanol (100 ml.) were refluxed for 2.5 hours. The resulting crystalline material was collectd and recrystallised from ethanol to give the title compound (29.1 g.), m.p. 201°-202° C. (Found: C, 47.9; H, 4.9; N, 6.3; C17H21IN2O3 requires C, 47.7; H, 4.9; N, 6.5%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04029801 |
| 出典データセット | uspto-grants-1977_06 |
| ORD ID | ord-12080977457145908188d689a8d8b499 |
| 出典メモ | uspto-grants-1977_06 |