Acetone → HCID 21427785、化合物
反応式
[CH3:1][C:2]([OH:11])([CH3:10])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH2:9].[CH3:12][C:13]([CH3:15])=O>C1C=CC=CC=1>[CH3:12][C:13]1([CH3:15])[O:11][C:2]([CH3:1])([CH3:10])[C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[NH:9]1参加物
4
実験手順
A solution of 15 g (0.1 mol) α,α-dimethyl-2-aminobenzyl alcohol and 5.7 g (0.1 mol) acetone in 120 ml of benzene was heated under reflux in a Dean-Stark trap for 3 hours. About 1.5 ml of water was separated from the reaction mixture. The benzene solution was then evaporated to give an oil which solidified on standing. Recrystallization from ethanol-water gave 5.2 g 2,2,4,4-tetramethyl-1,2-dihydro-4H-3,1-benzoxazine, as a white solid.
後処理
- temperatureunder reflux in a Dean-Stark trap for 3 hours
- customAbout 1.5 ml of water was separated from the reaction mixture
- customThe benzene solution was then evaporated
- customto give an oil which
- customRecrystallization from ethanol-water
出典と根拠
- ORDレコード
- ord-b6c8389db47b4922bf9498fc5ddefe47
- 出典データセット
- uspto-grants-1977_06
- 特許番号
- US04030906
反応ノート
読み込み中…