Ethyl formate → Hydrazinecarboxaldehyde, 2-(4-nitrophenyl)-

HRID 437282

反応式

HRID 437282 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][NH2:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH:12]([O-])=[O:13].[Na+].C(OCC)=O>C(O)C.C(O)=O>[CH:12]([NH:11][NH:10][C:7]1[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=1)=[O:13]

参加物

6

反応物 3

HCID 8025Ethyl formateHCID 2723810Sodium FormateHCID 3310889(4-Nitrophenyl)hydrazine

生成物 1

HCID 5008489Hydrazinecarboxaldehyde, 2-(4-nitrophenyl)-

試薬・触媒・溶媒 2

HCID 284Formic Acid溶媒HCID 702Ethanol溶媒

実験手順

4-Nitrophenylhydrazine (9.2 g, 0.06 mole), sodium formate (4.08 g, 0.06 mole), and ethyl formate (148 g, 2.00 moles) were mixed in ethanol (40 ml) and formic acid (30 ml). The mixture was heated on a steam bath; the volume of the mixture was reduced to approximately 100 ml by continued boiling. The hydrazide product crystallized out of the concentrated reaction mixture upon cooling. The product was filtered off, washed with ethanol, and dried. Yield 10.2 g (94%), m.p. 183°-185° C.

後処理

  1. temperatureThe mixture was heated on a steam bath
  2. customThe hydrazide product crystallized out of the concentrated reaction mixture
  3. temperatureupon cooling
  4. filtrationThe product was filtered off
  5. washwashed with ethanol
  6. customdried

出典と根拠

ORDレコード
ord-4763fac989e34e39a6a0a531a6d878a6
出典データセット
uspto-grants-1977_06
特許番号
US04030925

関連ノート

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