反応式
[CH3:1][C:2]1[CH2:9][S:8][CH:7]2[N:4]([C:5](=[O:11])[CH:6]2[NH2:10])[C:3]=1[C:12]([OH:14])=[O:13].ClC[CH2:17][C:18]([CH3:23])([CH3:22])[C:19]([O-:21])=[O:20].[C:24](OCC1CSC2N(C(=O)C2N)C=1C(O)=O)(=O)C.ClCOC(=O)CC>>[C:19]([O:21][CH2:24][O:13][C:12]([C:3]1[N:4]2[CH:7]([S:8][CH2:9][C:2]=1[CH3:1])[CH:6]([NH2:10])[C:5]2=[O:11])=[O:14])(=[O:20])[C:18]([CH3:23])([CH3:22])[CH3:17]参加物
5
反応物 4
生成物 1
実験手順
When the procedure of Example 8 appropriate amounts of 3-methyl-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid and chloromethylpivalate are substituted respectively for 3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid and chloromethylpropionate, 3-methyl-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid pivalyloxymethyl ester is obtained.
出典と根拠
- ORDレコード
- ord-8530d1a1e3d8492e9834d019af018b03
- 出典データセット
- uspto-grants-1977_06
- 特許番号
- US04031083
関連ノート
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