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Sodium Carbonate → 1,3-Bis[4-(2-benzoylhydrazino)phenyl]thiourea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 反応物 | 3,5-Dithia-4-thioxo-1,7-heptanedioic acid | HCID 80618 | — |
| 反応物 | N'-(4-Aminophenyl)benzohydrazide | HCID 20508846 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1,3-Bis[4-(2-benzoylhydrazino)phenyl]thiourea | HCID 21427817 | — |
反応手順
Sodium carbonate (4.65 g, 0.044 mole) was dissolved in a solvent mixture of water (95 ml) and ethanol (30 ml). Bis(carboxymethyl)trithiocarbonate (2.5 g, 0.011 mole) was added portionwise. Vigorous stirring of the reaction mixture was maintained until all solid was dissolved. It was then heated to 80°-85° C and 1-benzoyl-2-(4-aminophenyl)hydrazine (5.0 g, 0.022 mole) was added in one portion. Stirring and heating were maintained for 11/2 hour and the reaction mixture was then chilled. The solid was removed by filtration, washed and dried. Yield 2.05 g (37%), m.p. 185°-187° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04031127 |
| 出典データセット | uspto-grants-1977_06 |
| ORD ID | ord-d653f44eab4a495d95b8a2ae1a66dca6 |
| 出典メモ | uspto-grants-1977_06 |