Sulfuric Acid → Isopropyl acetoacetate
反応式
[C:1]([O:7][CH2:8][CH3:9])(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4].S(=O)(=O)(O)O.[CH:15](O)(C)C>>[C:1]([O:7][CH:8]([CH3:15])[CH3:9])(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4]参加物
4
実験手順
A solution of ethyl acetoacetate (250 g.) and concentrated sulphuric acid (10 ml.) in isopropanol (1500 ml.) was heated at reflux for 3 hours. The solvent was removed by distillation, the residue was neutralised by treatment with barium carbonate, filtered and distilled under reduced pressure to give isopropyl acetoacetate (139 g.), b.p. 79°-82° C./20 mm Hg, in the form of a colourless liquid.
後処理
- temperatureat reflux for 3 hours
- customThe solvent was removed by distillation
- filtrationfiltered
- distillationdistilled under reduced pressure
出典と根拠
- ORDレコード
- ord-b6056c242bd844a3a1b4bf0f9035f329
- 出典データセット
- uspto-grants-1977_06
- 特許番号
- US04032323
反応ノート
読み込み中…