Dibenzylamine → n,n-Dibenzylformamide

HRID 437859

反応式

HRID 437859 の反応式
[CH2:1]([NH:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:16](OC(=O)C)(=[O:18])C>C(O)=O>[CH:16]([N:8]([CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:18]

参加物

4

反応物 2

HCID 7656DibenzylamineHCID 7918Acetic Anhydride

生成物 1

HCID 221415n,n-Dibenzylformamide

試薬・触媒・溶媒 1

HCID 284Formic Acid溶媒

実験手順

To an ice-cold and vigorously stirred solution of dibenzylamine (918 g.) in 98% formic acid (105 ml.) is added dropwise, over 45 minutes, acetic anhydride (35 ml.). The resulting mixture is stirred for one hour at room temperature, then diluted with ice water (40 ml.) and kept overnight at 15° C. The solution is evaporated in vacuo to dryness and the residue extracted with ether. The ethereal solution is washed with water, dried over magnesium sulfate, filtered, and evaporated in vacuo to yield N-formyl-dibenzylamine (9.9 g.) as a white solid, m.p. 53°-54.5° C.

後処理

  1. waitkept overnight at 15° C
  2. customThe solution is evaporated in vacuo to dryness
  3. extractionthe residue extracted with ether
  4. washThe ethereal solution is washed with water
  5. dry with materialdried over magnesium sulfate
  6. filtrationfiltered
  7. customevaporated in vacuo

出典と根拠

ORDレコード
ord-8cf0564eba464f84a985114127fa7ac5
出典データセット
uspto-grants-1977_06
特許番号
US04032521

関連ノート

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