関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | 2-[4-(Dimethylamino)benzoyl]benzoic acid | HCID 88937 | — |
| 反応物 | 1,3-Benzenediamine, N1,N1,N3,N3-tetramethyl- | HCID 89715 | — |
| 生成物 | 3-(2,4-Bis(dimethylamino)phenyl)-3-(4-(dimethylamino)phenyl)phthalide | HCID 20440832 | — |
反応手順
A mixture of 2-(4-(dimethylamino)benzoyl)benzoic acid (26.8 g.), N,N.N', N'-tetramethyl-m-phenylenediamine (16.4 g.) and acetic anhydride (80 g.) was heated (to 95° C.) during one hour, cooled and poured into dilute hydrochloric acid. The resulting mixture was basified. Recrystallization of the resulting solid from a mixture of toluene and hexane afforded 3-(2,4-bis(dimethylamino)phenyl)-3-(4-(dimethylamino)-phenyl)phthalide (I: X= Y4 = (CH3)2N, Y2 = Z4 = Z5 = Z6 = Z7 = H) (m.p. 190°-194° C.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04032527 |
|---|
| 出典データセット | uspto-grants-1977_06 |
|---|
| ORD ID | ord-e068953078524751994921244ff37bfb |
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| 出典メモ | uspto-grants-1977_06 |
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