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Dimethyl Sulfoxide → 2-(p-Biphenylyl)-3-butyn-2-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethyl Sulfoxide | HCID 679 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | 4-Acetylbiphenyl | HCID 7113 | — |
| 生成物 | 2-(p-Biphenylyl)-3-butyn-2-ol | HCID 86734896 | — |
反応手順
To a solution of 46.6 g of p-phenylacetophenone in 250 ml. of dimethyl sulfoxide, there is added 65.5 g of lithium acetylide - ethylene diamine complex. After 18 hours at room temperature, the mixture is poured on 2 liters of iced water. The initial oil solidifies on standing, is filtered off and recrystallized from 150 ml of isopropyl alcohol to give 2-(p-biphenylyl)-3-butyn-2-ol, mp 75°-80° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04032580 |
| 出典データセット | uspto-grants-1977_06 |
| ORD ID | ord-efd70c0ac46345d78a20218445e27eac |
| 出典メモ | uspto-grants-1977_06 |