化工社化工社 化学情報印刷レポート · 研究参考用
Methanol → N-(5-carboxy-2,3,4,5-tetrahydroxy-pentyl)-L-(+)-glutamic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | L-Glutamic Acid | HCID 33032 | — |
| 反応物 | Glucuronic Acid | HCID 65041 | — |
| 触媒 | Nickel | HCID 935 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | N-(5-carboxy-2,3,4,5-tetrahydroxy-pentyl)-L-(+)-glutamic acid | HCID 54046356 | — |
反応手順
As starting material D-glucuronic acid and L-(+)-glutamic acid were used. The reductive amination was carried out using Raney nickel as a catalyst and heating for 2 hours to 50° C. and for 4 hours to 70° C. The product obtained had a melting point of 90° C. (with sintering) an RF -value of 0.70 (determined on DC-finished plates of silica gel G (Merck) with a transporting liquid made up of 70 parts by volume of methanol and 30 parts by volume of water).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04032676 |
| 出典データセット | uspto-grants-1977_06 |
| ORD ID | ord-91fdf7bb5232460c8b88feb0fe6abf61 |
| 出典メモ | uspto-grants-1977_06 |