化工社化工社 化学情報印刷レポート · 研究参考用
Benzhydrylamine → cis(+/-)-1-(Diphenylmethyl)-2-ethylazetidin-3-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzhydrylamine | HCID 7036 | — |
| 反応物 | (2R*)-2-[(1S*)-1-bromopropyl]oxirane | HCID 86648818 | — |
| 生成物 | cis(+/-)-1-(Diphenylmethyl)-2-ethylazetidin-3-ol | HCID 10038631 | 29% |
反応手順
The same operation as in Example (234b) was performed using (2R*)-2-[(1S*)-1-bromopropyl]oxirane obtained in Example (235a) (1.50 g, 9.09 mmol) and benzhydrylamine (1.57 mL, 9.09 mmol), to obtain 699 mg of the title compound as a pale yellow solid (29%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08536197B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-d3beea6e4def4d39ae80f2382e9a50cc |
| 出典メモ | uspto-grants-2013_09 |