Hydrochloric Acid → 3,5-Diamino-4-hydroxybenzoic acid dihydrochloride

反応式

[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([NH2:12])[C:10]=1[OH:11])[C:5]([OH:7])=[O:6].[ClH:13]>>[ClH:13].[ClH:13].[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([NH2:12])[C:10]=1[OH:11])[C:5]([OH:7])=[O:6]

参加物

反応物 2

HCID 313Hydrochloric Acid

HCID 133101HCID 133101、化合物

生成物 1

HCID 1331003,5-Diamino-4-hydroxybenzoic acid dihydrochloride収率 90%

実験手順

3,5-Diamino-4-hydroxybenzoic acid (2 g, 11.9 mmole) was dissolved in 6N hydrochloric acid (50 ml) and refluxed for 2 hours. The mixture was evaporated to dryness and the residue was treated with ethyl acetate (50 ml), filtered and dried to give 3,5-diamino-4-hydroxybenzoic acid dihydrochloride (2.58 g, 90%), m.p. 260°-262° C. (dec.) (lit. ref., Chemical Abstracts, 1908, 2379, m.p. 260° C. (dec)).

後処理

temperaturerefluxed for 2 hours
customThe mixture was evaporated to dryness
additionthe residue was treated with ethyl acetate (50 ml)
filtrationfiltered
customdried

出典と根拠

ORDレコード: ord-062adf94a77b4aec92be6e88e155f82a
出典データセット: uspto-grants-1996_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05514676

反応ノート

読み込み中…

参加物