4-(4-Phenyl-4-n-propyl-4-silacyclohexyl)cyclohexanone → 4-(4-(4-Fluorophenyl)-3-cyclohexenyl)-1-phenyl-1-n-propyl-1-silacyclohexane

関与物質

反応手順

In the same manner as in Example 1, 35.0 g of 4-(4-n-propyl-4-phenyl-4-silacyclohexyl)cyclohexanone were subjected to coupling reaction with 4-fluorophenylmagnesium chloride, followed by dehydration reaction in the presence of an acid catalyst to obtain 35.9 g of 4-(4-n-propyl-4-phenyl-4-silacyclohexyl)-1-(4-fluorophenyl)-1-cyclohexene (yield: 82%). The results of 1H-NMR analysis are shown below. 1H-NMR (CDCl3) δ:0.50-2.55 (23H, m), 5.90-6.14 (1H, m), 6.80-7.65 (9H, ppm

情報源と証拠