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Ethyl Acetate → 4,5-Dihydro-5-(4-aminobenzoyl)pyrrolo[1,2-a]quinoxaline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl Acetate | HCID 8857 | — |
| 反応物 | 4,5-Dihydro-5-(4-nitrobenzoyl)pyrrolo[1,2-a]quinoxaline | HCID 21837135 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 4,5-Dihydro-5-(4-aminobenzoyl)pyrrolo[1,2-a]quinoxaline | HCID 21837005 | — |
反応手順
A mixture of 1 mmol of 4,5-dihydro-5-(4-nitrobenzoyl)pyrrolo[1,2-a]quinoxaline in 10 ml of ethyl alcohol and 10 ml of ethyl acetate containing 0.2 g of 10% Pd/C is hydrogenated for 5 hours. The reaction mixture is filtered through a pad of diatomaceous earth. The filtrate is concentrated in vacuo to a solid which is purified by flash chromatography to give the desired product, m.p. 225°-228° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05516774 |
| 出典データセット | uspto-grants-1996_05 |
| ORD ID | ord-b70ed097f33e4358bb3adf6a67d02155 |
| 出典メモ | uspto-grants-1996_05 |