化工社化工社 化学情報印刷レポート · 研究参考用
Hydrogen Cyanide → Isophorone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrogen Cyanide | HCID 768 | — |
| 反応物 | Phosphoric Acid | HCID 1004 | — |
| 反応物 | Isophorone | HCID 6544 | — |
| 反応物 | HCID 10921347 | HCID 10921347 | — |
| 生成物 | Isophorone | HCID 6544 | — |
| 生成物 | 3-Cyano-3,5,5-trimethylcyclohexanone | HCID 99068 | — |
反応手順
To 622 g (4.5 mol) of isophorone in the presence of 4.14 g (0.02mol) of butyltrimethylammonium methylcarbonate there are added 288.3 g of a mixture of 3 mol of HCN and 1.5 mol of isophorone over a period of 120 min and at a temperature of 115° C. Following neutralization with 4 g of H3PO4 the mixture is distilled. There are obtained 424.3 g of isophorone and 478.3 g of 3-cyano-3,5,5-trimethylcyclohexanone. This is equivalent to a yield of 98.8% based on converted isophorone and 96.5% based on HCN used.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05516928 |
| 出典データセット | uspto-grants-1996_05 |
| ORD ID | ord-15a255fe33ea4c8bb3f29466a1da3a33 |
| 出典メモ | uspto-grants-1996_05 |