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HRID 440269作成日：2026年10月26日

1-(2-Hydroxyethyl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid → 1-(2-Hydroxyethyl)-6,8-difluoro-7-(5,6,7,8-tetrahydroimidazo[1,2-a]pyrazin-7-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

https://huagongshe.com/reaction/440269

反応式

関与物質

役割名称HCID仕込み量
反応物1-(2-Hydroxyethyl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidHCID 12770917—
反応物5,6,7,8-Tetrahydroimidazo(1,2-a)pyrazineHCID 13247046—
生成物1-(2-Hydroxyethyl)-6,8-difluoro-7-(5,6,7,8-tetrahydroimidazo[1,2-a]pyrazin-7-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acidHCID 15411481—

反応手順

Using 1-(2-hydroxyethyl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine, the same procedure as in Production Example 1 was followed to yield the title compound.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05519024
出典データセットuspto-grants-1996_05
ORD IDord-e9106df6c62a44f4a03e829cf9e6b4b4
出典メモuspto-grants-1996_05