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Thionyl Chloride → 6-(2-Thienyl)pyridine-3-carbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 6-(Thiophen-2-Yl)Pyridine-3-Carboxylic Acid | HCID 15411144 | — |
| 生成物 | 6-(2-Thienyl)pyridine-3-carbonyl chloride | HCID 17879033 | — |
反応手順
A mixture of 1.8 g of 6-(2-thienyl)pyridine-3-carboxylic acid in 50 ml of thionyl chloride is refluxed under dry conditions for 1 hour. The reaction mixture is evaporated to dryness and evaporated again from 50 ml of carbon tetrachloride to a residue. The residue is dissolved in 60 ml of methylene chloride and used further reactions.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05521173 |
| 出典データセット | uspto-grants-1996_05 |
| ORD ID | ord-91e25bf160764e81b0ace79c715a5053 |
| 出典メモ | uspto-grants-1996_05 |