Potassium Carbonate → N-(4-methoxycarbonylphenyl)-N-methyl-terephthalamic acid methyl ester

HRID 440819ノート

反応式

HRID 440819 の反応式
[Cl-].[CH3:2][O:3][C:4](=[O:14])[C:5]1[CH:13]=[CH:12][C:8]([C:9]([OH:11])=O)=[CH:7][CH:6]=1.[CH3:15][NH:16][C:17]1[CH:26]=[CH:25][C:20]([C:21]([O:23][CH3:24])=[O:22])=[CH:19][CH:18]=1.C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH3:2][O:3][C:4](=[O:14])[C:5]1[CH:6]=[CH:7][C:8]([C:9]([N:16]([C:17]2[CH:18]=[CH:19][C:20]([C:21]([O:23][CH3:24])=[O:22])=[CH:25][CH:26]=2)[CH3:15])=[O:11])=[CH:12][CH:13]=1

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 140375Methyl 4-methylaminobenzoateHCID 53442854Terephthalic acid monomethylester chloride

生成物 1

HCID 54006989N-(4-methoxycarbonylphenyl)-N-methyl-terephthalamic acid methyl ester

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

0.995 g of terphthalic acid monomethyl ester chloride and 0.756 g of methyl 4-(methylamino)-benzoate were dissolved in 25 ml of acetone and treated with 0.691 g of anhydrous potassium carbonate. The reaction mixture was stirred at room temperature for 30 hours and was evaporated. The residue was treated with water and the crystals were filtered off yielding N-(4-methoxycarbonyl-phenyl)-N-methyl-terephthalamic acid methyl ester in the form of colourless crystals, MS: m/z 327 (M+).

後処理

  1. customwas evaporated
  2. additionThe residue was treated with water
  3. filtrationthe crystals were filtered off

出典と根拠

ORDレコード
ord-156086967abd4369aeb0ce2767cee5af
出典データセット
uspto-grants-1996_05
特許番号
US05521160

反応ノート

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