M-Phenylenediamine → 3'-Acetoacetamidoacetoacetanilide

反応式

[CH2:1]=[C:2]1[O:6][C:4](=[O:5])[CH2:3]1.[C:7]1([NH2:14])[CH:12]=[CH:11][CH:10]=[C:9]([NH2:13])[CH:8]=1>>[C:2]([CH2:3][C:4]([NH:13][C:9]1[CH:8]=[C:7]([CH:12]=[CH:11][CH:10]=1)[NH:14][C:4](=[O:5])[CH2:3][C:2](=[O:6])[CH3:1])=[O:5])(=[O:6])[CH3:1]

参加物

反応物 2

HCID 7935M-Phenylenediamine

HCID 12661Diketene

生成物 1

HCID 986453'-Acetoacetamidoacetoacetanilide

実験手順

The process of the invention for the preparation of compounds of formula I wherein R' is ##STR11## comprises reacting diketene with m-phenylenediamine to obtain m-(acetylacetamido)-acetylacetanilide which is reacted with methyl orthoformate and then heated to obtain m-(3'-methoxycrotonylamino)-3 -methoxy-crotonanilide.

後処理

customThe process of the invention for the preparation of compounds of formula I wherein R'

出典と根拠

ORDレコード: ord-0ced766b34944393abe6248bf33050fa
出典データセット: uspto-grants-1977_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04039316

反応ノート

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