Cyclohexylamine → HCID 135623126、化合物

反応式

[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=O)[CH2:9][S:10]([CH3:12])=[O:11].[CH:14]1([NH2:20])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH:14]1([N:20]=[C:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[OH:1])[CH2:9][S:10]([CH3:12])=[O:11])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

参加物

反応物 2

HCID 7965Cyclohexylamine

HCID 578088HCID 578088、化合物

生成物 1

HCID 135623126HCID 135623126、化合物収率 96%

実験手順

A solution of 2'-hydroxy-2-(methylsulfinyl)acetophenone (15 g, 0.076 mole) in cyclohexylamine (75 ml) was stirred at 90° for 6 hrs. The reaction mixture was cooled and poured into petroleum ether (1 l.). The product was filtered off and washed with hexane to give yellow crystals (20.2 g, 96%), mp 133°-134°.

後処理

temperatureThe reaction mixture was cooled
filtrationThe product was filtered off
washwashed with hexane

出典と根拠

ORDレコード: ord-3bd5de1f7d0e45aaa0df02cc8067b423
出典データセット: uspto-grants-1977_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04039579

反応ノート

読み込み中…

参加物