Ethylamine → Trans 3-chloro-N-ethylcinnamamide

HRID 441562ノート

反応式

HRID 441562 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)/[CH:5]=[CH:6]/[C:7](Cl)=[O:8].[CH2:13]([NH2:15])[CH3:14]>C1C=CC=CC=1.CCOCC>[Cl:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)/[CH:5]=[CH:6]/[C:7]([NH:15][CH2:13][CH3:14])=[O:8]

参加物

5

反応物 2

HCID 6341EthylamineHCID 11008963(2E)-3-(3-chlorophenyl)prop-2-enoyl chloride

生成物 1

HCID 6015846Trans 3-chloro-N-ethylcinnamamide

試薬・触媒・溶媒 2

HCID 241Benzene溶媒HCID 3283Diethyl Ether溶媒

実験手順

Trans 3-chlorocinnamoyl chloride (4.4 g) in dry benzene (75 ml) was allowed to react with an excess of ethylamine in dry ether (75 ml) according to the procedure of Example 2. Trans 3-chloro-N-ethylcinnamamide, m.p. 87°-88° C., was obtained which had NMR, IR, and elemental analysis consistent with this structure.

出典と根拠

ORDレコード
ord-6d07ba44392049e0bcb0fec8c65e091e
出典データセット
uspto-grants-1977_08
特許番号
US04041071

反応ノート

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