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Benzyl Bromide → 2-Benzyl-6-methoxyisoquinolinium bromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Bromide | HCID 7498 | — |
| 反応物 | 6-Methoxyisoquinoline | HCID 11040978 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 2-Benzyl-6-methoxyisoquinolinium bromide | HCID 21418213 | — |
反応手順
6-Methoxyisoquinoline (1.6 g) and benzyl bromide (2 ml) in acetone (75 ml) were heated under reflux for 1 hour. The mixture was diluted with ether and cooled to 0°. The solid was filtered off and recrystallised from methanol/ether, and had m.p. 155°-158°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04042697 |
| 出典データセット | uspto-grants-1977_08 |
| ORD ID | ord-a515023c47354e99bfa7c2376c17c423 |
| 出典メモ | uspto-grants-1977_08 |