Diisopropylamine → Diisopropylammonium 2-propyl-5-thiazolecarboxylate

HRID 442494

反応式

HRID 442494 の反応式
[CH2:1]([C:4]1[S:5][C:6]([C:9]([OH:11])=[O:10])=[CH:7][N:8]=1)[CH2:2][CH3:3].[CH:12]([NH:15][CH:16]([CH3:18])[CH3:17])([CH3:14])[CH3:13]>CC(C)=O>[CH2:1]([C:4]1[S:5][C:6]([C:9]([O-:11])=[O:10])=[CH:7][N:8]=1)[CH2:2][CH3:3].[CH:12]([NH2+:15][CH:16]([CH3:18])[CH3:17])([CH3:14])[CH3:13]

参加物

4

反応物 2

HCID 7912DiisopropylamineHCID 65773Tizoprolic Acid

生成物 1

HCID 21415066Diisopropylammonium 2-propyl-5-thiazolecarboxylate収率 90%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

4.45 Grams of 2-propyl-5-thiazolecarboxylic acid (obtained in Example II) are dissolved in 120 cc of acetone and 2.62 gm of diisopropylamine are added. The solvent is evaporated off under low pressure and the crystals thus obtained are recrystallized from isopropyl ether. The diisopropylammonium 2-propyl-5-thiazolecarboxylate is obtained in the form of colorless crystals, soluble in water and in alcohol, melting at 120° C. (Yield: 90%).

後処理

  1. customThe solvent is evaporated off under low pressure
  2. customthe crystals thus obtained
  3. customare recrystallized from isopropyl ether

出典と根拠

ORDレコード
ord-378c935309a3447ca2cda4daca4c765c
出典データセット
uspto-grants-1977_08
特許番号
US04045567

関連ノート

読み込み中…