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Pyridine → Tert-butyl 1-chloroethyl carbonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | tert-Butanol | HCID 6386 | — |
| 反応物 | 1-Chloroethyl chloroformate | HCID 521305 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Tert-butyl 1-chloroethyl carbonate | HCID 13557091 | — |
反応手順
In a reactor cooled to +5° C., there are introduced 600 ml of dicloromethane, 43.7 g (0.59 mole) of tert-butanol and 94.7 g (0.66 mole) of α-chloroethyl chloroformate. 57 g (0.72 mole) of pyridine are then added dropwise and with stirring while the temperature is maintained at between 10° and 20° C. The mixture is stirred for 4 hours at room temperature.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04725680 |
| 出典データセット | uspto-grants-1988_02 |
| ORD ID | ord-eb26a125028f488199001eac7c1803da |
| 出典メモ | uspto-grants-1988_02 |