化工社化工社 化学情報印刷レポート · 研究参考用
Trichloroacetyl chloride → 2-(Trichloroacetyl)pyrrole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trichloroacetyl chloride | HCID 6420 | — |
| 反応物 | Pyrrole | HCID 8027 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 2-(Trichloroacetyl)pyrrole | HCID 321487 | — |
反応手順
To a solution of trichloroacetyl chloride (160.7 mmoles) in ethyl ether (26 ml) there is added, dropwise over a period of 3 hours, a solution of pyrrole (149 mmoles) in ethyl ether (83 ml). After stirring for a further hour, a solution of potassium carbonate (94 mmoles) in water (39 ml) is added dropwise. The phases are separated and the organic phase is dried over sodium sulphate and filtered. Active carbon is added to this organic phase. After stirring for 5 minutes, the organic phase is filtered and evaporated to dryness to yield the title product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08541412B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-c606efcc6d174fd5af17b1eca1f8b113 |
| 出典メモ | uspto-grants-2013_09 |