化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 4'-Nonanoyloxybiphenyl-4-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 2-Dimethylaminopyridine | HCID 21885 | — |
| 反応物 | Nonanoyl chloride | HCID 69819 | — |
| 反応物 | 4'-Hydroxy-4-biphenylcarboxylic acid | HCID 301556 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | 4'-Nonanoyloxybiphenyl-4-carboxylic acid | HCID 13668451 | 86.3% |
反応手順
4'-Hydroxybiphenyl-4-carboxylic acid (3.5 g) and triethylamine (2.4 g) were dissolved in dichloromethane (30 ml). Nonanoyl chloride (4.3 g) and dimethylaminopyridine (0.2 g) were added to the solution, and the mixture was stirred at room temperature for about 20 hours. Dilute hydrochloric acid was added thereto, and the organic layer was separated in a separating funnel. The solvent was removed by evaportaion, and the residue was dried after washing with n-hexane to give the titled compound (5 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05891359 |
| 出典データセット | uspto-grants-1999_04 |
| ORD ID | ord-0fbb1e06db2441929e7b81c2113f4d94 |
| 出典メモ | uspto-grants-1999_04 |