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Phosphorus oxide (P4O10) → Methyl 4,5-Methylenedioxy-2-(3-methyl-4-nitrobenzoyl)phenylacetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phosphorus oxide (P4O10) | HCID 14812 | — |
| 反応物 | 3-Methyl-4-nitrobenzoic acid | HCID 18370 | — |
| 反応物 | Methyl 2-(1,3-dioxaindan-5-yl)acetate | HCID 266588 | — |
| 溶媒 | 1,2-Dichloroethane | HCID 11 | — |
| 生成物 | Methyl 4,5-Methylenedioxy-2-(3-methyl-4-nitrobenzoyl)phenylacetate | HCID 53912114 | — |
反応手順
The title compound was prepared from methyl 3,4-methylenedioxyphenylacetate (2.1 g, 11 mmol) in ClCH2CH2Cl (70 mL), 3-methyl-4-nitrobenzoic acid (3.7 g, 20 mmol) and P2O5 (6 g) as an oily solid (1.4 g, 3.9 mmol, 35%). 1H NMR (CDCl3) 7.99 (d, J=8.2, 1H), 7.74 (s, 1H), 6.69 (d, J=8.2, 1H), 6.84 (s, 1H), 6.83 (s, 1H), 6.07 (s, 2H), 3.86 (s, 2H), 3.64 (s, 3H), 2.63 (s, 3H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05891871 |
| 出典データセット | uspto-grants-1999_04 |
| ORD ID | ord-40d6e34c8e0a41b88484cf648bb50b89 |
| 出典メモ | uspto-grants-1999_04 |