関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethanolamine | HCID 700 | — |
| 反応物 | 4-Nitrophenethyl bromide | HCID 79266 | — |
| 生成物 | 2-[2-(4-Nitro-phenyl)-ethylamino]-ethanol | HCID 22722744 | — |
反応手順
A mixture of 1-(2-bromo-ethyl)-4-nitro-benzene (86.9 mmoles) and 2-amino-ethanol (869 mmoles) is heated at 150° C. under microwave activation for 10 minutes. The reaction mixture is evaporated to dryness and the residue obtained is purified on silica gel (SiO2; gradient DCM/MeOH) to yield the title product, which is used directly in the next Step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08541412B2 |
|---|
| 出典データセット | uspto-grants-2013_09 |
|---|
| ORD ID | ord-2b4fbf189855456f819977f42058ce7e |
|---|
| 出典メモ | uspto-grants-2013_09 |
|---|
