関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | [1-(triphenylmethyl)-1H-imidazol-4-yl]methanol | HCID 382182 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 4-(Chloromethyl)-1-trityl-1H-imidazole | HCID 2763176 | — |
反応手順
The product from Step B is dissolved in chloroform and cooled to 0° C. under nitrogen. Thionyl chloride (molar equivalent) is added slowly via syringe. The reaction is stirred for 30 min, and extracted with sodium bicarbonate solution. The organic phase is dried over magnesium sulfate, filtered and concentrated to provide the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05891889 |
|---|
| 出典データセット | uspto-grants-1999_04 |
|---|
| ORD ID | ord-20695b29fecf4994adf4ae877b640bc6 |
|---|
| 出典メモ | uspto-grants-1999_04 |
|---|
