Ammonia → 2-Amino-5-(4'-hydroxy-2',3'-dimethyl anilino)-1,4-benzoquinone

HRID 443510

反応式

HRID 443510 の反応式
[NH2:1][C:2]1[CH:3]=[C:4]([OH:10])[CH:5]=[CH:6][C:7]=1[O:8]C.N.OO.[CH3:14][C:15]1[C:20]([CH3:21])=[C:19]([NH2:22])[CH:18]=[CH:17][C:16]=1[OH:23]>O.CC(C)=O>[NH2:1][C:2]1[C:7](=[O:8])[CH:6]=[C:5]([NH:22][C:19]2[CH:18]=[CH:17][C:16]([OH:23])=[C:15]([CH3:14])[C:20]=2[CH3:21])[C:4](=[O:10])[CH:3]=1

参加物

7

反応物 4

HCID 222AmmoniaHCID 784Hydrogen PeroxideHCID 765424-HydroxyxylidineHCID 203418413-Amino-4-methoxyphenol

生成物 1

HCID 234675392-Amino-5-(4'-hydroxy-2',3'-dimethyl anilino)-1,4-benzoquinone

試薬・触媒・溶媒 2

HCID 180Acetone溶媒HCID 962Water溶媒2 回

実験手順

0.01 mole (1.39 g) of 3-amino-4-methoxy phenol is dissolved in 100 cc of water to which have been added 50 cc of acetone and 10 cc of ammonia (22° Be'). To this solution there are added 100 cc of H2O2 (20 volumes) and immediately thereafter, with good agitation, 0.01 mole (1.37 g) of 2,3-dimethyl-4-amino phenol in suspension in 100 cc of water. The resulting reaction mixture is agitated for three hours at which time it is filtered to recover the 2-amino-5-(4'-hydroxy-2',3'-dimethyl anilino)-1,4-benzoquinone which is first washed with water and then with acetone. It is dried for 8 hours under a vacuum with a boiling water bath and is chromatographically pure, melting at 320° C.

後処理

  1. customThe resulting reaction mixture
  2. filtrationis filtered
  3. customto recover the 2-amino-5-(4'-hydroxy-2',3'-dimethyl anilino)-1,4-benzoquinone which
  4. washis first washed with water
  5. customIt is dried for 8 hours under a vacuum with a boiling water bath

出典と根拠

ORDレコード
ord-12a17b0f09644c8699ba61af9adf0973
出典データセット
uspto-grants-1981_04
特許番号
US04260749

関連ノート

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