化工社化工社 化学情報印刷レポート · 研究参考用
2,6-Dimethylaniline → Methyl N-(2,6-dimethylphenyl)-DL-alaninate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,6-Dimethylaniline | HCID 6896 | — |
| 反応物 | Methyl 2-bromopropionate | HCID 95576 | — |
| 反応物 | Sodium Bicarbonate | HCID 516892 | — |
| 生成物 | Methyl N-(2,6-dimethylphenyl)-DL-alaninate | HCID 94555 | 79.6% |
反応手順
Furthermore, the reaction of 2,6-dimethylaniline at 120°-125° C., in the presence of sodium bicarbonate as an acid-binding agent, with a three-fold molar excess of methyl 2-bromopropionate has been disclosed in U.S. Pat. No. 4,008,066. With this process, N-(1'-methoxycarbonylethyl)-2,6-dimethylaniline is obtained in a yield of 79.6% of theory.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04260782 |
| 出典データセット | uspto-grants-1981_04 |
| ORD ID | ord-6f962d8509e74197826dff60cf811abf |
| 出典メモ | uspto-grants-1981_04 |