2-Naphthol → 2-(2-Naphthoxy)ethanol

HRID 443635ノート

反応式

HRID 443635 の反応式
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[OH:11].Br[CH2:13][CH2:14][OH:15].C[O-].[Na+]>C(O)C>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[O:11][CH2:13][CH2:14][OH:15]

参加物

5

反応物 3

HCID 86632-NaphtholHCID 108982-BromoethanolHCID 10942334Sodium Methoxide

生成物 1

HCID 71312-(2-Naphthoxy)ethanol

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 14.4 g. of 2-naphthol, 12.1 g. of 2-bromoethanol and 5.9 g. of sodium methoxide in 100 ml. of ethanol is allowed to stand two days at room temperature. The solvent is removed under vacuum and the residue extracted with ether. The ether extract is washed with water, dried (magnesium sulfate) and the solvent removed under vacuum to give crystals, m.p. 65°-70° C.

後処理

  1. customThe solvent is removed under vacuum
  2. extractionthe residue extracted with ether
  3. extractionThe ether extract
  4. washis washed with water
  5. dry with materialdried (magnesium sulfate)
  6. customthe solvent removed under vacuum
  7. customto give crystals, m.p. 65°-70° C.

出典と根拠

ORDレコード
ord-e44b96c5bbf042d2aa00fb49b8d546f4
出典データセット
uspto-grants-1981_04
特許番号
US04260816

反応ノート

読み込み中…