Acetyl chloride → 1-(4-Propylphenyl)ethan-1-one

HRID 443680

反応式

HRID 443680 の反応式
[Cl-].[Cl-].[Cl-].[Al+3].[C:5](Cl)(=[O:7])[CH3:6].[CH3:9][CH2:10][CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1>C(=S)=S>[CH3:9][CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([C:5]([CH3:6])=[O:7])=[CH:14][CH:13]=1

参加物

5

反応物 3

HCID 6367Acetyl chlorideHCID 7668PropylbenzeneHCID 6451240Aluminum(III) Chloride2 回

生成物 1

HCID 762361-(4-Propylphenyl)ethan-1-one

試薬・触媒・溶媒 1

HCID 6348Carbon Disulfide溶媒2 回

実験手順

Crushed anhydrous aluminium trichloride (1.28 mole) was suspended in dry carbon disulphide (348 ml). Acetylchloride (1.1 mole) and n-propylbenzene (1.0 mole) was dissolved in dry carbon disulphide (348 ml) and added to the suspension of aluminium trichloride under anhydrous conditions. The mixture was then left to stir overnight. The solvent was distilled from the reaction mixture and the viscous residue poured onto crushed ice and stirred for 0.5 hours. The product was extracted into ether and the extract washed with water and dried (Na2SO4). The ether was removed by distillation and the oily residue distilled. The product had mpt 132° C. at 0.1 mm Hg.

後処理

  1. waitThe mixture was then left
  2. distillationThe solvent was distilled from the reaction mixture
  3. additionthe viscous residue poured
  4. customonto crushed ice
  5. stirringstirred for 0.5 hours
  6. extractionThe product was extracted into ether
  7. washthe extract washed with water
  8. dry with materialdried (Na2SO4)
  9. customThe ether was removed by distillation
  10. distillationthe oily residue distilled

出典と根拠

ORDレコード
ord-183b8cdcf9c34c478cd67ba56997d885
出典データセット
uspto-grants-1981_04
特許番号
US04261651

関連ノート

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