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Bromopyruvic Acid → 3-(Bromomethyl)-1,2-dihydroquinoxalin-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bromopyruvic Acid | HCID 70684 | — |
| 反応物 | 1,2-Diaminobenzene (D4, 98%) | HCID 10772950 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 3-(Bromomethyl)-1,2-dihydroquinoxalin-2-one | HCID 286254 | — |
反応手順
O-phenylenediamine (1.0 g., 0.0092 mol.) was dissolved in tetrahydrofuran (50 ml.) and 3-bromopyruvic acid (1.7 g., 0.0102 mol.) added. The reaction mixture was stirred at room temperature for one hour, during which time the product precipitated as a yellow solid. The product was collected by filtration and crystallized from methylene chloride. (0.91 g., m.p. 221°-223° (dec.) 41%)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04262123 |
| 出典データセット | uspto-grants-1981_04 |
| ORD ID | ord-a422bb2a765c42ceb676a1d2d0df4fbd |
| 出典メモ | uspto-grants-1981_04 |