Ammonia → 2,3-Dihydro-3,3-dimethylbenzofuran-5-carboxylic acid amide
反応式
[CH3:1][C:2]1([CH3:14])[C:6]2[CH:7]=[C:8]([C:11](Cl)=[O:12])[CH:9]=[CH:10][C:5]=2[O:4][CH2:3]1.[NH3:15]>>[CH3:1][C:2]1([CH3:14])[C:6]2[CH:7]=[C:8]([C:11]([NH2:15])=[O:12])[CH:9]=[CH:10][C:5]=2[O:4][CH2:3]1参加物
3
実験手順
The product of stage (b) (4.2 g) was added dropwise to excess aqueous ammonia with stirring and ice cooling. After 1 hour the white precipitate was filtered off and recrystallised from ethanol to give 1.1 g of title product, mp 136°-138° C.
後処理
- filtrationAfter 1 hour the white precipitate was filtered off
- customrecrystallised from ethanol
出典と根拠
- ORDレコード
- ord-c9111588a20349739d8406f5176bc31e
- 出典データセット
- uspto-grants-1981_04
- 特許番号
- US04263037
反応ノート
読み込み中…