Hydrochloric Acid → 2,6-Di-tert-butyl-4-(chloromethyl)phenol

HRID 444107

反応式

HRID 444107 の反応式
[OH:1][C:2]1[C:9]([C:10]([CH3:13])([CH3:12])[CH3:11])=[CH:8][C:5]([CH2:6]O)=[CH:4][C:3]=1[C:14]([CH3:17])([CH3:16])[CH3:15].[ClH:18]>CCCCCC>[OH:1][C:2]1[C:9]([C:10]([CH3:13])([CH3:12])[CH3:11])=[CH:8][C:5]([CH2:6][Cl:18])=[CH:4][C:3]=1[C:14]([CH3:17])([CH3:16])[CH3:15]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 6929Butylated hydroxymethylphenol

生成物 1

HCID 123786012,6-Di-tert-butyl-4-(chloromethyl)phenol

試薬・触媒・溶媒 1

HCID 8058Hexane溶媒

実験手順

176 grams of 4-hydroxy-3,5-di-tert-butyl-benzyl alcohol was slurried in 350 ml of hexane. 240 cc of concentrated HCl was added to the slurry and stirred overnight. The two phases were allowed to separate and the hexane phase washed twice with water. The dried hexane was then extracted with magnesium sulfate and filtered. Rotofilm evaporation yielded 168 grams of product--a pungent yellow liquid.

後処理

  1. customto separate
  2. washthe hexane phase washed twice with water
  3. extractionThe dried hexane was then extracted with magnesium sulfate
  4. filtrationfiltered
  5. customRotofilm evaporation

出典と根拠

ORDレコード
ord-0c6429c18bae40c796f71c081f89e807
出典データセット
uspto-grants-1981_04
特許番号
US04263154

関連ノート

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