Sodium Cyanide → HCID 23464477、化合物
反応式
Br[CH2:2][C:3]1[CH:18]=[CH:17][C:6]2[C:7](=[O:16])[NH:8][C:9]3[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=3[S:11][C:5]=2[CH:4]=1.[C-:19]#[N:20].[Na+]>CN(C)C=O>[C:19]([CH2:2][C:3]1[CH:18]=[CH:17][C:6]2[C:7](=[O:16])[NH:8][C:9]3[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=3[S:11][C:5]=2[CH:4]=1)#[N:20]参加物
4
実験手順
Dissolve 6.4 gm. of the bromide of Step B in 75 cc. of dimethylformamide and add 2.95 gm. of sodium cyanide. Stir the mixture at room temperature for 1.5 hours. Dilute with 600 cc. of water and extract three times with ether. Wash the combined organics with water, dry and strip to a solid residue. Triturate in hexane and recover the solid by filtration.
後処理
- dissolutionDissolve 6.4 gm
- additionDilute with 600 cc
- extractionof water and extract three times with ether
- washWash the combined organics with water
- customdry
- customTriturate in hexane
- customrecover the solid
- filtrationby filtration
出典と根拠
- ORDレコード
- ord-ef01500807144ce8b99c663e8e7dd45b
- 出典データセット
- uspto-grants-1981_04
- 特許番号
- US04263207
反応ノート
読み込み中…