関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1-Chloro-4-nitrobenzene | HCID 7474 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 4-Methylphenethyl alcohol | HCID 95294 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | 1-Methyl-4-[2-(4-nitrophenoxy)ethyl]benzene | HCID 5142926 | 89.4% |
反応手順
To a solution of 65% sodium hydride (1.1 g, 0.03 mole) in dimethylsulfoxide (30 ml) were added 2-(4-methylphenyl)ethyl alcohol (VIII) (2.72 g, 0.02 mole) and 4-nitrochlorobenzene (IX: X=Cl) (3.15 g, 0.02 mole). After heating to 30° C. for 5 hours with stirring, the reaction mixture was treated in the same manner as in Example 12 to obtain 4.6 g of 4-[2-(4-methylphenyl)ethoxy]nitrobenzene (VI) as white crystals (yield, 89.5%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04263219 |
|---|
| 出典データセット | uspto-grants-1981_04 |
|---|
| ORD ID | ord-68c853b477e7413a8acfb7aa86d78478 |
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| 出典メモ | uspto-grants-1981_04 |
|---|
