p-nitrophenol sodium salt → 1-Methyl-4-[2-(4-nitrophenoxy)ethyl]benzene

HRID 444177

反応式

HRID 444177 の反応式
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9]Br)=[CH:4][CH:3]=1.[N+:11]([C:14]1[CH:19]=[CH:18][C:17]([O-:20])=[CH:16][CH:15]=1)([O-:13])=[O:12].[Na+]>CN(C)C=O>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][O:20][C:17]2[CH:18]=[CH:19][C:14]([N+:11]([O-:13])=[O:12])=[CH:15][CH:16]=2)=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 13214p-nitrophenol sodium saltHCID 5706804-Methylphenethyl bromide

生成物 1

HCID 51429261-Methyl-4-[2-(4-nitrophenoxy)ethyl]benzene収率 73.8%

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

2-(4-Methylphenyl)ethyl bromide (X: X=Br) (10 g, 0.05 mole) and sodium 4-nitrophenolate (XI) (8.1 g, 0.05 mole) were added to dimethylformamide (60 ml), and the mixture was reacted at 90° C. for 5 hours. Thereafter, the reaction mixture was treated in the same manner as in Example 12 to obtain 9.5 g of 4-[2-(4-methylphenyl)ethoxy]nitrobenzene (VI) as white crystals (yield, 73.9%).

後処理

  1. customthe mixture was reacted at 90° C. for 5 hours
  2. additionThereafter, the reaction mixture was treated in the same manner as in Example 12
  3. customto obtain

出典と根拠

ORDレコード
ord-600c5b91b211400d851f7be8f6e0f06e
出典データセット
uspto-grants-1981_04
特許番号
US04263219

関連ノート

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